Transurethral MR-HIFU for the treatment of localized prostate cancer

Methods In contrast to transrectal approaches, transurethral ultrasound applicators are simple in construction and designed for single use. Delivery of ultrasound from within the prostate gland avoids passing energy through sensitive structures, and enables rapid tissue ablation. Tissue is coagulated radially outwards from the urethra, with the depth of treatment controlled based on the temperatures measured with MR thermometry. One of the challenges with transurethral HIFU is generating coagulation to the boundary of the prostate gland where tumors are often located.